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A study of the immune response in murine experimental malaria, with special reference to the effects of South African medicinal plants, artesunate and chloroquine

The role of pro-inflarrnnatory cytokines (TNF and IFN-y) in a murine experimental malaria model for cerebral malaria is reported in this thesis. Wild type and receptor knockout mice (IFN-y deficient mice (IFN-l") and TNF-a/fr1- double deficient) were infected with Plasmodium berghei ANKA {PbA). PbA...

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Bibliographic Details
Main Author: Gumede, Bonginkosi
Other Authors: Folb, Peter
Format: Thesis
Language:English
English
Published: Division of Clinical Pharmacology 2025
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