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Using single nucleus RNA-seq to determine the effect of immunosuppression on the transcriptional activity of resident CNS cells in a mouse model of CNS-TB
Tuberculosis (TB) is the leading infectious cause of death worldwide and is particularly prevalent in South Africa. Central Nervous System TB (CNS-TB), specifically TB Meningitis (TBM) is the deadliest complication of the disease. Given the high co-prevalence of HIV and CNS-TB, many transcriptional...
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| Language: | English English |
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Department of Human Biology
2025
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