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Development of 3D multicellular liver organoids derived from human induced pluripotent stem cells to model antiretroviral therapy induced liver injury

Introduction: The liver is an essential organ in the body responsible for the synthesis of serum proteins, biotransformation, and detoxification of xenobiotic drugs. Drug cytotoxicity studies have been conducted using cancer-derived cell lines which are inferior. In the present study, we developed a...

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Bibliographic Details
Main Author: Maepa, Setjie Welcome
Other Authors: Ndlovu, Hlumani
Format: Thesis
Language:English
English
Published: Department of Integrative Biomedical Sciences (IBMS) 2025
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