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The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation

Background: The use of tramadol in the management of chronic pain has recently become controversial. Amidst rising reports on potential for abuse and its exclusion from latest international guidelines, the conduct of a Medicine Usage Evaluation (MUE) of the drug is relevant to inform future training...

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Main Author: Muissa, Mbombo Marie Astrid
Other Authors: Parker, Romy
Format: Thesis
Language:English
English
Published: Department of Anaesthesia and Perioperative Medicine 2026
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access_status_str Open Access
author Muissa, Mbombo Marie Astrid
author2 Parker, Romy
author_browse Muissa, Mbombo Marie Astrid
Parker, Romy
author_facet Parker, Romy
Muissa, Mbombo Marie Astrid
author_sort Muissa, Mbombo Marie Astrid
collection Thesis
description Background: The use of tramadol in the management of chronic pain has recently become controversial. Amidst rising reports on potential for abuse and its exclusion from latest international guidelines, the conduct of a Medicine Usage Evaluation (MUE) of the drug is relevant to inform future training and practice. Methods: A cross sectional retrospective descriptive chart review of the use of tramadol for the year 2021 was conducted at the Groote Schuur Chronic Pain Management Clinic (CPMC). A total of 104 folders were reviewed. Descriptive statistics summarise the data. Results: The average person with chronic pain who was being prescribed tramadol included in this MUE was female, receiving a disability grant and in their late fifties (57.28y ±12.32). A median of three comorbidities (IQR 4) were recorded in the folders. The median duration of clinic attendance was 10,5 years (IQR 11,5). Chronic spinal pain (61%) was the most common diagnosis. Atypical tramadol dosages were recorded. Only 4% of patients attributed improvement of their pain to tramadol therapy. Good prescription practices were adhered to for the majority of criteria, the key domains with shortcomings were in documentation of the severity of pain, documentation of assessment for potential drug interactions, and documentation of referral for non-pharmacological treatments. Conclusion: The MUE on the use of tramadol at the Groote Schuur CPMC was characterised by good prescription practices with regard to documentation on patient profile, pain diagnosis and management. We recommend the use of standardised protocols for follow up visits and moving to electronic records. The lack of improvement associated with tramadol therapy reported by patients was concerning. In such circumstances, we support the use of a patient-centred tapering strategy with atypical dosages not exceeding the maximum recommended daily dose and the integration of non-pharmacological treatments.
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institution University of Cape Town (South Africa)
language English
eng
last_indexed 2026-06-10T12:32:42.829Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2026
publishDateRange 2026
publishDateSort 2026
publisher Department of Anaesthesia and Perioperative Medicine
publisherStr Department of Anaesthesia and Perioperative Medicine
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spelling oai:open.uct.ac.za:11427/42548 The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation Muissa, Mbombo Marie Astrid Parker, Romy Flint, Margot Groote Schuur Pain management clinic Background: The use of tramadol in the management of chronic pain has recently become controversial. Amidst rising reports on potential for abuse and its exclusion from latest international guidelines, the conduct of a Medicine Usage Evaluation (MUE) of the drug is relevant to inform future training and practice. Methods: A cross sectional retrospective descriptive chart review of the use of tramadol for the year 2021 was conducted at the Groote Schuur Chronic Pain Management Clinic (CPMC). A total of 104 folders were reviewed. Descriptive statistics summarise the data. Results: The average person with chronic pain who was being prescribed tramadol included in this MUE was female, receiving a disability grant and in their late fifties (57.28y ±12.32). A median of three comorbidities (IQR 4) were recorded in the folders. The median duration of clinic attendance was 10,5 years (IQR 11,5). Chronic spinal pain (61%) was the most common diagnosis. Atypical tramadol dosages were recorded. Only 4% of patients attributed improvement of their pain to tramadol therapy. Good prescription practices were adhered to for the majority of criteria, the key domains with shortcomings were in documentation of the severity of pain, documentation of assessment for potential drug interactions, and documentation of referral for non-pharmacological treatments. Conclusion: The MUE on the use of tramadol at the Groote Schuur CPMC was characterised by good prescription practices with regard to documentation on patient profile, pain diagnosis and management. We recommend the use of standardised protocols for follow up visits and moving to electronic records. The lack of improvement associated with tramadol therapy reported by patients was concerning. In such circumstances, we support the use of a patient-centred tapering strategy with atypical dosages not exceeding the maximum recommended daily dose and the integration of non-pharmacological treatments. 2026-01-13T07:19:59Z 2026-01-13T07:19:59Z 2025 2026-01-12T08:25:45Z Thesis / Dissertation Masters MMed http://hdl.handle.net/11427/42548 en eng application/pdf Department of Anaesthesia and Perioperative Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Groote Schuur
Pain management clinic
Muissa, Mbombo Marie Astrid
The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation
thesis_degree_str Master's
title The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation
title_full The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation
title_fullStr The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation
title_full_unstemmed The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation
title_short The use of tramadol at the Groote Schuur chronic pain management clinic (CPMC): a medicine usage evaluation
title_sort use of tramadol at the groote schuur chronic pain management clinic cpmc a medicine usage evaluation
topic Groote Schuur
Pain management clinic
url http://hdl.handle.net/11427/42548
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