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Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury
Background: Peritoneal dialysis (PD) has long been a mainstay of acute kidney injury (AKI) management in children of all ages, and it remains the most commonly used modality in low-income regions, where continuous kidney replacement therapy (CKRT) is not widely available. Compared to extracorporeal...
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| Format: | Thesis |
| Language: | English English |
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Department of Paediatrics and Child Health
2026
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| _version_ | 1867614465272315904 |
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| access_status_str | Open Access |
| author | Nourse, Peter |
| author2 | Morrow, Brenda |
| author_browse | Morrow, Brenda Nourse, Peter |
| author_facet | Morrow, Brenda Nourse, Peter |
| author_sort | Nourse, Peter |
| collection | Thesis |
| description | Background: Peritoneal dialysis (PD) has long been a mainstay of acute kidney injury (AKI) management in children of all ages, and it remains the most commonly used modality in low-income regions, where continuous kidney replacement therapy (CKRT) is not widely available. Compared to extracorporeal therapies, PD has lower clearance as well as lower and less precise fluid removal. We previously demonstrated increased ultrafiltration and clearances using continuous flow peritoneal dialysis (CFPD) in children with AKI, however the technique described required expensive high-volume CKRT pumps to circulate fluid, as well as high level technical expertise, limiting its utility in resource-constrained settings. Identifying safe, effective and low-cost techniques for CFPD may improve access to dialysis for children with AKI in low-resource settings. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/42622 |
| institution | University of Cape Town (South Africa) |
| language | English eng |
| last_indexed | 2026-06-10T12:52:28.479Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2026 |
| publishDateRange | 2026 |
| publishDateSort | 2026 |
| publisher | Department of Paediatrics and Child Health |
| publisherStr | Department of Paediatrics and Child Health |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/42622 Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury Nourse, Peter Morrow, Brenda Continuous Flow Peritoneal Dialysis Peritoneal dialysis Acute Kidney Injury Protein removal Glucose absorption Dialysate salt removal Children Background: Peritoneal dialysis (PD) has long been a mainstay of acute kidney injury (AKI) management in children of all ages, and it remains the most commonly used modality in low-income regions, where continuous kidney replacement therapy (CKRT) is not widely available. Compared to extracorporeal therapies, PD has lower clearance as well as lower and less precise fluid removal. We previously demonstrated increased ultrafiltration and clearances using continuous flow peritoneal dialysis (CFPD) in children with AKI, however the technique described required expensive high-volume CKRT pumps to circulate fluid, as well as high level technical expertise, limiting its utility in resource-constrained settings. Identifying safe, effective and low-cost techniques for CFPD may improve access to dialysis for children with AKI in low-resource settings. 2026-01-20T09:30:54Z 2026-01-20T09:30:54Z 2025 2026-01-15T11:01:31Z Thesis / Dissertation Doctoral PhD http://hdl.handle.net/11427/42622 en eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town |
| spellingShingle | Continuous Flow Peritoneal Dialysis Peritoneal dialysis Acute Kidney Injury Protein removal Glucose absorption Dialysate salt removal Children Nourse, Peter Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury |
| thesis_degree_str | Doctoral |
| title | Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury |
| title_full | Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury |
| title_fullStr | Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury |
| title_full_unstemmed | Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury |
| title_short | Gravity assisted continuous flow peritoneal dialysis (CFPD) in children with acute kidney injury |
| title_sort | gravity assisted continuous flow peritoneal dialysis cfpd in children with acute kidney injury |
| topic | Continuous Flow Peritoneal Dialysis Peritoneal dialysis Acute Kidney Injury Protein removal Glucose absorption Dialysate salt removal Children |
| url | http://hdl.handle.net/11427/42622 |
| work_keys_str_mv | AT noursepeter gravityassistedcontinuousflowperitonealdialysiscfpdinchildrenwithacutekidneyinjury |