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Resistance to antimicrobial agents in bifidobacteria
Includes bibliographical references (leaves 95-106).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Molecular and Cell Biology
2014
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| _version_ | 1867613409111965697 |
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| access_status_str | Open Access |
| author | Price, Claire Emile |
| author2 | Abratt, Valerie Rose |
| author_browse | Abratt, Valerie Rose Price, Claire Emile |
| author_facet | Abratt, Valerie Rose Price, Claire Emile |
| author_sort | Price, Claire Emile |
| collection | Thesis |
| description | Includes bibliographical references (leaves 95-106). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/4323 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:35:41.246Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/4323 Resistance to antimicrobial agents in bifidobacteria Price, Claire Emile Abratt, Valerie Rose Reid, Sharon J Cell Biology Includes bibliographical references (leaves 95-106). For bifidobacteria to survive and achieve colonisation, they have to interact with inhibitory host-produced substances such as bile salts. Another aspect which should be studied is the safety of the probiotic bacterium and risks of acquisition of genes for resistance to antimicrobial agents. Although bifidobacteria exhibit resistance to a wide range of antibiotics, little is known about the molecular basis for this resistance. The aim of this project was, therefore, to investigate the molecular mechanisms responsible for the resistance to antibiotics and bile salts observed in bifidobacteria, and more specifically, to determine whether efflux systems are involved in this resistance. Five Bifidobacterium spp. were exposed to a range of antimicrobial agents. These included ethidium bromide, the bile salt sodium glycocholate, and a range of antibiotics. 2014-07-30T17:41:42Z 2014-07-30T17:41:42Z 2005 Master Thesis Masters MSc http://hdl.handle.net/11427/4323 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Cell Biology Price, Claire Emile Resistance to antimicrobial agents in bifidobacteria |
| thesis_degree_str | Master's |
| title | Resistance to antimicrobial agents in bifidobacteria |
| title_full | Resistance to antimicrobial agents in bifidobacteria |
| title_fullStr | Resistance to antimicrobial agents in bifidobacteria |
| title_full_unstemmed | Resistance to antimicrobial agents in bifidobacteria |
| title_short | Resistance to antimicrobial agents in bifidobacteria |
| title_sort | resistance to antimicrobial agents in bifidobacteria |
| topic | Cell Biology |
| url | http://hdl.handle.net/11427/4323 |
| work_keys_str_mv | AT priceclaireemile resistancetoantimicrobialagentsinbifidobacteria |