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Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Human Biology
2014
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| _version_ | 1867613159622180864 |
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| access_status_str | Open Access |
| author | Van Heerden, Esther |
| author2 | Vicatos, George |
| author_browse | Van Heerden, Esther Vicatos, George |
| author_facet | Vicatos, George Van Heerden, Esther |
| author_sort | Van Heerden, Esther |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/6012 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:43.046Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/6012 Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro Van Heerden, Esther Vicatos, George Kidson, Susan Medicine Includes abstract. Includes bibliographical references. Aseptic loosening of artificial joints occurs due to the loss of implant fixation. By implementing a 3D porous structure at the bone-implant interface, the ingrowth of bone will permit better and stronger interlocking of the implant to prevent loosening. In this study, it is hypothesized that the seeding of 3D scaffolding structures with mesenchymal stem cells (MSCs) will improve the potential for osseointegration of the implants, as the existing bone may be more inclined to unite with developing bone than with the implant substrate. Titanium-6 Aluminium-4 Vanadium (Ti64) is one of the most commonly used implant materials. Heat treatment of Ti64 was seen in tests done at the University of Cape Town to further improve against implant failure by vastly improving the materials strength and reducing debris formation. Thus the aim of this study was to investigate the effects the heat treatment of Ti64 would have on the capabilities of seeded MSCs in vitro. 2014-08-05T12:30:26Z 2014-08-05T12:30:26Z 2014 Master Thesis Masters MSc http://hdl.handle.net/11427/6012 eng application/pdf Department of Human Biology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Van Heerden, Esther Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro |
| thesis_degree_str | Master's |
| title | Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro |
| title_full | Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro |
| title_fullStr | Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro |
| title_full_unstemmed | Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro |
| title_short | Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro |
| title_sort | osseointegration potential for heat treated 3d ti6al4v scaffolds seeded with mysenchymal stem cells in vitro |
| topic | Medicine |
| url | http://hdl.handle.net/11427/6012 |
| work_keys_str_mv | AT vanheerdenesther osseointegrationpotentialforheattreated3dti6al4vscaffoldsseededwithmysenchymalstemcellsinvitro |